The pedestrianised shopping precinct is a successful pre-WW2 design, adopted in numerous locations to rebuild war ravaged city centres in Europe and elsewhere. Key to attracting cyclists is the design of safe corridors between residential areas and the centre, which I suppose means attracting the support of transport planners as well as architects.
Multi-purpose buildings for cycle-related activity have aready been adapted........I'm not sure how much ground-up design has taken place. Many cities would benefit from a bike shop/cafe/ repair centre/ hire centre/secure parking place. This would seem like a good base from which to run repair clinics, renovation workshops and so on, which could also benefit wheelchair users and soforth.........
-am I understanding you correctly?