What's your wife's take on wine?
There are some terrific wineries and sillystring-roads around Paso Robles, which is where I'm taking my bike (bicycle) the weekend after next if the weather don't stink.
Riding on Big Sur is pretty much a nightmare when RV's are allowed on the road, but I've heard magical legends about landslides during winter (which are perfectly passable on foot) which have closed Hwy 1 and turned it into a post-Ebola-virus paradise for bicycles.