Originally Posted by LeeG

same, also you don't say what kind of bike it is or your cycling history but it's a road saddle and if you aren't accustomed to road riding position it takes as much technique and conditioning as everything else. Most modern saddles are designed to reduce perineum pressure but there's no way around it, you sit on a bicycle seat. If you're sitting more upright with bars above seat position you might need a wider saddle. I used to ride on regular narrow saddles all my life but as I got fatter my bars moved up to 1" below the saddle. I got a new saddle with the perineum relief but it felt too narrow, according to Specialized butt-o-meter I fit the 135mm wide saddle but it just felt too narrow. I got the 143mm and it's perfect.
As far as your question "how long does it take to get used to this?" depends a lot on what "this" is. When I was first touring in my late teens and early 20's I simply tolerated the discomfort and would ride the whole day. Didn't even wear bike shorts. Then when I got into regular road riding and training/racing all day riding really was a pain, pain and overcoming it was a big part of the riding. Then when I tapered off 3 1/2 hours was pretty much all I ever road at one time. I wasn't into the pain anymore. Now I'll get off the bike after 90minutes and stretch. So modify your expectations for "this" and you can get used to it pretty soon. Oh, get out of the saddle more often.