All of the designated bike routes on the SF Bike Map:
http://www.sfbike.org/download/SF_Bike_Map_2010.pdf
If you're living in SF, it's a good idea to buy this map for $10, or join the San Francisco Bike Coalition ($35) and get it for free. As you can see, it gives plenty of information about the city, including street grades local bike shops, and designated bike routes.
Lastly, if you haven't killed Twin Peaks yet--do it.