Paws are definitely something to keep watching. Paw pads are not designed for running on pavement or loose rock. Check your dog's feet after a long run and look for wear to the pads or injuries between the pads from debris.
If cracks or sores develop consider boots, or tuffpaws and consult your veterinarian. OTOH pavement does a good job of trimming nails.
Most dogs will be fine, but some dogs have tougher feet than others. YMMV.