The new NW Point bus to/from PDX
[Amtrak and Greyhound are only a block apart, they stop in both]
to Astoria, Seaside, Cannon Beach, is quite nice these days.
http://www.oregon-point.com/nw_point.html
Amtrak to Eugene, goes East over the Cascades to Klamath Falls from there
away from the coast, .. Points south, Mt Shasta, Sacramento, Emeryville..