There's a bike path that extends from the Inner Harbor up to North Tonawanda. 15 miles or so one way I think. Delaware park for "go fast and turn left" kind of rides.
Google maps has bicycle directions as well, and highlights the bike paths in green. Also, there is this:
http://www.gbnrtc.org/planning/bikeped/master-plan/
Not all paths/lanes are there yet, but it points them out clearly.