FWIW, I've used Ergons (grips) exclusively since they first became available ... 05 or 06 (can't remember)?
In any event ... for me, at least, they have proven very effective. YMMV.
Positioned correctly, they address both carpal tunnel and ulnar neuropathy issues (the two forms of what used to be called 'cyclist's palsy') when cycling with flat bars. They help with any disposition to carpal tunnel symptoms by working against any tendency to 'drop your wrist', and to ulnar nerve problems by dispersing pressure on the palm over a wide area (as well as by damping vibration).
I use the standard ones (can't remember the number) with separate bar-ends. The latter help as well, by permitting (a la tops-to-hoods on drop bars) rotation of the wrist for variation and variation in torso angle. Have had no issues with hand pain/numbness whatsoever, on rides of any distance, since adopting these grips. Oh, and I'm old (60) and arthritic!