Takes tim e to get fomfy. Heck, I put 30,000 miles on my Lemond roadies with no problem then switched over to a Madone and the thing was twitchy and made me uncomfy with the handling. Month later and 300 miles it's very natural once again.
Expect your butt to be uncomfy after a couple of miles as well. It takes saddle time to break in your butt. An upgraded saddle vs stock saddle and good shorts help though.