There's a big difference between superficial butt pain (typical saddle sores) and sore sit-bones.
I only get saddle sores on rides over 200km - and then, only sometimes. I just use standard cycling pants and the saddle my bike came with, and forced myself to HTFU. Seemed to work - or maybe I was just lucky.
But for all the miles I've done, I still get sore sit-bones at the end of long rides. Not sure what can be done about that...