My doctor said that Androgel (for low T) will increase the size of my prostate and possibly bump up my PSA number. Annual physicals and semi annual checkups, all with blood work keeps things in perspective. You are a FOOL not to get a colonoscopy as soon as one can be prescribed. It provides an absolute baseline. You don't want to try cycling with a colostomy bag duck taped to your side. Ask my brother.
Chris