FWIW: The term "saddle sore" usually refers to an infection in the skin and are treated/prevented with antibiotics or topical anti-bacterials. Chafing and abrassions are something else, and of course are dealt with differently. Properly fitting (snug) cycling shorts tend to hold the chamois in firm contact with the skin so that it moves with the skin rather than against. Some find it helpful to use a chamois cream product to reduce friction in folds of skins or in places where rubbing is inevitable.