I like 50-34 on a friction shifted bike, where you spend most of your time on the 50, and only drop to the 34 in a significant climb.
I like 53-39 on an index shifting crank, because the shifting is crisper (14 tooth vs 16 tooth jump). It, IMO, makes the front crisp and fast, with less overlap and less reluctance to use it.
I liked a 50-36 crank I had, to get the crisp shift between rings, but ended up using the 36 so rarely that I went to a single 46 tooth chainring, and loved the 1x9.
Mostly I ride a single speed now, 47x16, and have done all of the same rides that I did with 9, 18, or 20 gear combinations with 1. So I guess that I am gear agnostic.
So, long story short, I don't think anyone can recommend gearing for anyone else, at least in a meaningful manner.