I ride a 50/34 and either an 11-32 or 11-28 in the back. If there's stuff that's more than 7% for any stretch I'll go with the 11-32, but for say a long climb that is pretty constant grade (like mt hamilton) I'll use an 11-28 and be fine. I don't like killing my knees grinding up 10%+ grades even if it's for a short time. With an 11-32 I can downshift to stand on really steep stuff. Living next to the Santa Cruz mountains you end up climbing a lot, so you don't see many people riding standards out here.
I'll ride the inner for a lot of riding and if I need to just use the smaller part of the cassette. I find myself in the big ring at the top of a hill. I didn't like shifting between rings because you get that weird gap you have to cover with 2-3 shifts in the back but with electronic shifting it's pretty fast to pull that off.