I like my hoods to be perpendicular to the angle that my arms come down off of my body so my wrists do not have to twist downwards at my palms and pinch the ulnar nerve in my wrists when gripping the hoods. I have nerve issues with my wrists from years of racing motorcycles off-road and having undiagnosed lyme disease for a number of years which precipitated septic arthritis which presents mostly in my load-bearing joints as well as my wrists. I position my drop-bar brakes up higher than most people do and get a lot of folks comment that my "brake levers are too high." But I don't have them angled quite that much up/back.