I should expliain, what is truly significant about these specs is the change they make to ones position. 1-3 create a position that allows an open hip angle for good breathing and elbows that support your upper body weight comfortably.
A good position on a tri bike will save you about 3-5 minutes on a 40k time trial, funny because most people when being fitted put the seat back and about 5cms of spacers under their stem completely discarding the use of a tri bike. This is what differentiates a TT bike from a Tri bike, position.
Aero tubing and shaping will save you 1-2 minutes and wheels will give you 30-90 seconds.