The frame is just a small percentage of the weight of the fully outfitted bike. I have an Air Friday that in its current configuration weighs around 22 lb.
If I swapped the Selle Anatomica leather saddle for a carbon-shell saddle and replaced all the 2004-vintage 9-speed Ultegra alloy components with current carbon Shimano/SRAM/Campagnolo groupset, the bike would drop down in the 16–17 lb. range, at the cost of several thousand dollars. I don't bother because I ride with a hydration pack (containing gear) that easily adds 10 lb. to what I'm propelling with my legs