A 26in wheel is the opposite of undesirable. In fact Surly started offering all of their larger sized bikes in 26in due to customer demand.
I have a 56 LHT in 700c. I wish the option for the 26 had been available at the time.
I also wish I had disc brakes. But that wasn't available either. Built my trucker in 2008.
I think I'm talking myself into a new Trucker. Hmmmm....