I'm a big fan of the Madone. I've had mine for about half a year now, have about 2500 miles on it so far, and love it. I test rode the Pilot and the Roubaix when shopping, but I liked the Madone significantly better. For me, an important difference was the geometry. The Madone, with its racing heritage, has a more aggressive geometry that will get you down and out of the wind better if you have the flexibility to deal with it. When I first got the Madone I was actually a little uncomfortable riding for long periods of time in the drops. But my flexibility has improved with time, and it now feels very good.
I can't say bad things about the Roubaix, however. My wife has one, and she loves it. Never been on a Litespeed Toscani, so no nothing useful to offer there.
I reckon that you're not going to go too far wrong with any of these, but given your stated objectives for the bike, the Madone sounds like a good choice if it feels comfortable on a test ride.