tufos are great, but damned pricey... and you need tubular rims, unless you go for the tufo tubular clinchers. the pro of tubbies are that you can run them at insanely low pressure. the cons are that they are expensive, require some expertise to set right [i always left dribbles of glue everywhere], and when you get a flat, it's not just the tube...
i've been running a set of maxxis larsens this year and, frankly, they're the best tires i've ever had.