I Take glucosamine - chondroitin & MSM in a liquid. 1 shot a day. Keeps the joints at bay. I get it at BJ's for 19.00 a bottle 1 months worth. When I first started to get healthy my doc told me to quit it because of cholesterol, after a month off of it my joints started to hurt when I would get up in the morning. I started back on it and can tell the difference. It origanley took about 1 month to start working. My Cholesterol is now at 163 total diet made the difference on that.