I recently bought a Trek 7300. I've only managed to put 83 miles on it so far because the weather here in NW PA simply refuses to co-operate with me. I can tell you one thing, though. The stock Bontrager "comfort spring" saddle is garbage !! After one 11 mile ride, that thing came off and my trusty old Serfas "split up the middle" saddle went on. Those things make all the difference because they put the weight on your sit bones instead of, well, you know ...... Some padding in your clothing will help too.
As far as your handlebar/wrist dilemma? All I can say is experiment. If a bike shop wants a sale bad enough, they should work with you as far as stem/bar adjustments. Crank forward sounds like it may be a good option. Try one !!