If somone here doesn't produce some lit on knee issues, go to the training and nutrition forum. I'm sure someone has an article or two.
Many strong riders and climbers use compact cranks. Lance is famous for his high rev style winning the TDF. Not to knock your ability but why would you want to push a fixie up a hill? Unless you're a super climber. I've seen some do it, but usually about 150 lb riders with super strong legs. I really think that you would end up damaging the knees if you don't get into excellent shape first.
Unless like you said, it's for a joy ride to the Quickie Mart and back!