Hey -- first, they are great bikes -- I have an 06 and close to 2500 miles so far. Love it.
Second, the 2006 at least is a wee bit odd in sizing. I'm 6'3 and ended up with a 58 -- I have a relatively short inseam (i think 35.5), and the 60 didn't have enough standover to be comfy. Also, the BB is a little higher, and the top tube a little longer than the seat tube...so even though I'd go 60 on a roadie, i went 58 for the JTS. Sometimes standing up on a very steep rise, I feel like my legs get close to the bars, but i have no toe overlap or comfort issues riding 60-80 miles. I have about 5 inches of seatpost showing, and it's about an inch above the bars. It does feel like a bit "alive", which is likely the more aggressive angles. I like that; you may prefer the newer slacker approach (I wonder if the major is still more aggressive?).
Bottom line -- ride them, try them, get what feels the best,