You might also want to try Hammer Nutrition's Tissue Rejuvenator, which is glucosamine, chondroitin, MSM as well as a few other ingredients not found in most GCMSM preparations. My left elbow was giving me periodic problems which necessitated wearing an elastic brace several days a week. Started taking a glucosamine/MSM combo from Costco that helped somewhat, but I was still having to use the brace every 10 days or so. After a few weeks of that I got the Tissue Rejuvenator and after taking it for a week quit wearing the brace altogether--haven't needed it for 5 weeks now. Sorry if I sound like a shill but I'm quite pleasantly surprised at the difference this stuff has made.