You have the possibility for either 406 mm wheels or 451 mm wheels. I have a road single speed bicycle set for 5.3 gain ratio (451 mm wheels, 170 mm crank length, 52 teeth chain ring, 15 teeth sprocket) and I am fairly please with the "do it all drive train setting". I suppose you can feel a more road like response on a 451 mm wheel than on a 406 wheel.
A picture on me riding the 65 km around the Sea of Galilee in 2008.
http://www.shvoong.co.il/imageFromEv...ate=01/11/2008
PS: If you fellas want to see more pictures of the event
http://www.shvoong.co.il/imageFromEv...owSearch=False