Originally Posted by
fuzz2050
What exactly is your motivation in doing this? If you just want the security of a 'slow release' skewer, there are bolt on skewers that take the place of your quick release. It would save you a fair bit of time and effort to just use one of those.
It stiffens up the rear end significantly over a quick release is why many mountain bikers do this...
+1 on what dirtdrop suggested