I own both a full size commuter and a 16" folder, and although I don't ride big commuting miles, I notice that small tires are more costly than 700c tires, and I have read other posts from folder commuters that they go through a lot of tires and rims. My take is if multi-mode commuting works for you, or you have parking problems, get a folder. If you do a lot of grocery hauling, or a lot of mileage, go with a full-size bike.