Not much fun.
Headwinds are a constant for all riders. Set your teeth and start grinding (or find some wheels to suck ).
Tailwinds...What needs to be said?
Crosswinds are vexing when riding one-handed. I can lay my left arm across my flats but have no grip. My right arm fatigues from fighting to hold a line and coming off a bridge (or hill) with a strong cross-wind is no fun at all.
I can't think of much in the way of a solution but would love some ideas.