as noted recently in another thread, a lot of people here are quick to point out "i always stop at stop signs".
when i'm driving a car/van/truck, i ALWAYS do a full stop at stop signs. when i'm on a bike, not always.
the thing is, if i get rear-ended in a car in that situation it's unlikely to be any worse than filling out some forms. if i get rear-ended on a bike in that same situation, it could be pretty bad.
aside from cross-traffic (this includes pedestrians!), i think the biggest influence on whether or not i full-stop at a stop sign is the whether or not there's any traffic behind me, and what "vibe" i get from the driver behind me.