Spoked to Death
Join Date: Jul 2004
Location: Boulder, CO
Bikes: Salsa La Cruz w/ Alfine Internal 8-speed, Scattante Ultegra roadie, Maserati fixie conversion
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I wouldn't drill out the flanges.. The tolerances are really close, and there isn't really space for a safe drill, not to mention the stress problems your drill press would create because it wouldn't be a perfectly smooth hole.
I'd look into other things, like the alternate lacing patterns, to create a different look. Three leading three trailing is almost as strong as 3x, and just as easy to make.