Training & Nutrition - L-Glutamine

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View Full Version : L-Glutamine


jfm
07-13-05, 08:34 AM
Hello all. Do any of you use L-Glutamine?


shimanopower
07-13-05, 08:51 AM
420 mg per serving in the endurox r4 recovery drink I use. Glutamic acid + l glutamine 2.6g/serv. This is the best recovery drink I've ever used.

smoke
07-13-05, 08:53 AM
it's in the protein shake i make every day


53-11_alltheway
07-13-05, 10:14 AM
I used to use it. I think it's pretty much hype though. It's touted for it's cell volumizing effects, but not much of this stuff gets past the stomach.

Creatine works as advertised, but it's not much use for endurance athletes.

Tien
07-13-05, 10:30 AM
i wonder if lance uses it? (or other premier riders...)

lauren
07-13-05, 10:38 AM
L-glutamine is the most plentiful amino acid in skeletal muscle. Part of the contractile proteins.

531Aussie
07-13-05, 10:43 AM
420 mg per serving in the endurox r4 recovery drink I use. Glutamic acid + l glutamine 2.6g/serv. This is the best recovery drink I've ever used.

how much $$$?

^*^BATMAN^*^
07-13-05, 10:50 AM
Creatine works as advertised, but it's not much use for endurance athletes.

Creatine is a rip off. I dought anyone here would be using it. But Creatine forces water into muscle cells to promote faster bigger muscle growth. You can get the same effect by drinking ALOT of water......whats cheaper, a 1L Nalgene bottle, or ginormous bottles of Creatine???

53-11_alltheway
07-13-05, 11:10 AM
Creatine is a rip off. I dought anyone here would be using it. But Creatine forces water into muscle cells to promote faster bigger muscle growth. You can get the same effect by drinking ALOT of water......whats cheaper, a 1L Nalgene bottle, or ginormous bottles of Creatine???

If creatine is a ripoff what do you call L-glutamine?

With creatine at least there are plenty of double blind placebo controlled studies you can look up on Pubmed . L-glutamine has been shown to do nothing when taken orally.(it only works intravenously in hospital patients in a catabolic state)

Creatine does more than force water into cells (which it does as a side effect by osmosis). Creatine is the precursor of creatine phosphate which is the the first form of energy muscle uses under anaerobic conditions.

It really does work for anaerobic work (which is pretty worthless for endurance cyclists). Back when I was doing really heavy lifting I noticed the poundages I could use in the 5-7 rep range were higher by a noticeable margin. Most other stuff I use seems to do nothing in contrast.

KrisPistofferson
07-13-05, 11:25 AM
Your troll strength is strong.
:roflmao:

Nashville Man
07-13-05, 11:34 AM
Now are going to say worthwhile stuff like you did above or are you keep getting banned.

If this guy used to be in high school why do his posts reflect the intellect and maturity of a 13 or 14 year old?

sparknote_s
07-13-05, 12:45 PM
If you use creatine that puts water into cells which makes the cell volumizing effect you are using OUTDATED products. Meaning, newer and better stuff is available. Creatine ethyl ester is what is good nowadays, no cell volumizing (which is bad). Basically creatine increases your ATP. Anyways cyclist don't use creatine...

Now glutamine on the other hand would be useful for cyclists. It stops muscle catabolism (right word?). It is useful to take before you go to bed, because it will help you keep muscle that breaks down when you sleep. You could also take it before hard workouts, to keep glutamine that is stripped from your muscles normally in intense workouts. Not sure what other side affects would be, since I mostly know only weight lifters who use it before workouts.

shimanopower
07-13-05, 02:34 PM
how much $$$?

I buy it on sale for $30 dollars for a 5 pound/28 serving bottle.

late
07-13-05, 02:56 PM
If you want to try Glutamine without spending a bucket of dough,
Walmart has Glutamine tablets for 2 or 3 bucks.

You can buy gluten in bulk at health food stores for about $3 a pound. Gluten has a ton
of glutamine. I put a little extra in the bread and pancakes I make.
I have even been known to sneak some into brownies :eek:

shimanopower
07-13-05, 03:04 PM
If you want to try Glutamine without spending a bucket of dough,
Walmart has Glutamine tablets for 2 or 3 bucks.

You can buy gluten in bulk at health food stores for about $3 a pound. Gluten has a ton
of glutamine. I put a little extra in the bread and pancakes I make.
I have even been known to sneak some into brownies :eek:

why bother to buy it seperate? alot of products have it already in it.

late
07-13-05, 06:23 PM
It's cheap and effective.

53-11_alltheway
07-13-05, 06:48 PM
It's cheap and effective.

How is it effective? [Some of you guys should consider working for supplement companies marketing departments].

The thing about supplements is that a lot of them are snake oil. Sup[llement industry is great about bending studies which are remotely applicable and then manipulating them to fit their own agenda. Unless it is proven to work through double blind placebo controlled studies the theorectical benefits are meaningless.

A lot of this stuff when it's tested is found not to do anything.

The claims about glutamine's effectiveness by the supplement industry come from studies were glutamine was injected directly into the bloodstream via the intravenous route in high dosages. If was found to work well in catabolic ICU patients when used this way. Do you plan on shooting this stuff up?

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed [I just did a search of glutamine and exercise and I didn't come up with much at all.]

TexasGuy
07-14-05, 05:47 AM
53-11, while you have a very valid point, backing it with with research from NIH is in my honest opinion not a good way to go. :p From my experience, the NIH will disprove virtually anything they think may help somebody with some random study, while a decade studies, with double blind placebo etc, performed by universities and medical centers around the world/usa will prove otherwise.

I agree there is alot of marketing BS around supplements and sometimes they work in and of themselves as placebos as our bodies have shown this ability. It would definitely be nice if there was better studies and less involvement from sides who have a stake in some sort of outcome. I will however repeat that for some reason NIH seems to have something completely against all supplements and in my opinion, thus using their "findings" would be as wrong as using some study funded by somebody else had something to gain in a positive study.

53-11_alltheway
07-14-05, 05:50 AM
53-11, while you have a very valid point, backing it with with research from NIH is in my honest opinion not a good way to go. :p From my experience, the NIH will disprove virtually anything they think may help somebody with some random study, while a decade studies, with double blind placebo etc, performed by universities and medical centers around the world/usa will prove otherwise.

I agree there is alot of marketing BS around supplements and sometimes they work in and of themselves as placebos as our bodies have shown this ability. It would definitely be nice if there was better studies and less involvement from sides who have a stake in some sort of outcome. I will however repeat that for some reason NIH seems to have something completely against all supplements and in my opinion, thus using their "findings" would be as wrong as using some study funded by somebody else had something to gain in a positive study.

Where did I say NIH anywhere in my post?

I'm talking any double blind placebo controlled experiment from pretty much anyone (that would be better than extraploating a study done on ICU patients with high dose glutamine intravenously). Creatine has 100's of studies on Pubmed that says it improves anaerobic strength. Where are the oral glutamine studies?

TexasGuy
07-14-05, 05:51 AM
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed [I ju

I was not stating that your statement had any invalidity, I was merely pointing out my lack of trust of a nih.gov url used to back up a statement about a supplementary's effectiveness.

53-11_alltheway
07-14-05, 05:52 AM
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed [I ju

I was not stating that your statement had any invalidity, I was merely pointing out my lack of trust of a nih.gov url used to back up a statement about a supplementary's effectiveness.

link is not working. Studies are not from NIH anyway. Just because it's on there doesn't mean it was NIH funded.

Most of the stuides in Pubmed that have to do with sports nutrition are in no way connected to the NIH. Pubmed is just a collection of abstracts from the major peer reviewed scientific journals.

If it is a legitimate peer reviewed scientific journal you'll find it in Pubmed.

53-11_alltheway
07-14-05, 05:59 AM
while a decade studies, with double blind placebo etc, performed by universities and medical centers around the world/usa will prove otherwise.



These studies you are refering to are in Pubmed. (done at universities and medical centers)

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15707376&query_hl=2

Here is a review article on creatine from the Journal of Sports medicine.

Show me something like that for oral glutamine. It doesn't have to be the actual study, a review article will be fine.

Body2big
07-14-05, 07:04 AM
I am not saying this is any type of proof but here is some more info on Glutamine.

http://www.bodybuilding.com/store/glutamine.html

http://www.bodybuilding.com/fun/inmag6.htm

Shawn

53-11_alltheway
07-14-05, 07:10 AM
I am not saying this is any type of proof but here is some more info on Glutamine.

http://www.bodybuilding.com/store/glutamine.html

http://www.bodybuilding.com/fun/inmag6.htm

Shawn

I've been reading Bodybuilding magazines for a few years.

In these magazines Glutamine is considered a staple supplement, but you have to take this with a grain of salt when it comes from a bodybuilding magazines because all their advertising revenue comes from supplement makers.[Notice all the glutamine products that website sells in above link]

I got suckered into buying all kinds of crap when I believed what was in those magazines.

You are probably better off taking whey protein than glutamine if you care about money. It's a complete protein source that's cheap and gives everything you need.

TexasGuy
07-14-05, 07:11 AM
Unfortunately they reference scientific studies that appear to be non-existant. They are way too biased to be taken into consideration although they seem to be echoing what one study I saw done on amino acids showed. Intense body building and taking of a 4 amin-acids caused a major deteoriation in the immune system. I do not remember what they said was used to supplement it but I think the study concluded that it did successfully combat it.

53-11_alltheway
07-14-05, 07:20 AM
This is how I feel about Nutrition threads in the road forum....
http://www.chs.org/graphcoll/images/1995_36_1304.jpg

TexasGuy
07-14-05, 07:22 AM
:p

I think 40 -50 years from now we will look back and realize we were guinea pigs for the next couple of generation.

sindrella1
04-10-09, 11:30 PM
Hello all. Do any of you use L-Glutamine?

Hi! I have some information about L-Glutamine which I want to share with all of you.

L-Glutamine is energy sources utilized by rapidly proliferating cells. Glutamic acid the most abundant amino group in the human brain. L-Glutamine and Glutamine Powder plays a vital role to building and maintenance of muscle tissue.
more detail please visit: http://www.nutrovita.com/store/l-glutamine.htm

I hope this information will be useful for you.

Carbonfiberboy
04-11-09, 11:12 AM
OP: You probably mean straight L-Glutamine, not what comes as a fraction in whey protein, etc. Yes, I add a heaping teaspoon to each of the two bottles of 6% carbo solution I drink the day before a special ride, thinking it helps a bit with recovery and such like. Don't know if it works, but I have good rides when I do it, and it sure is cheap. When I'm going to be extra ruined, I'll also add some to my homemade recovery drink, on the advice of a CTS coach. I also add 5g creatine to my recovery drink, on same advice, since I'm a vegetarian. I am not a double-blind trial.

SSP
04-11-09, 11:42 PM
Hi! I have some information about L-Glutamine which I want to share with all of you.

L-Glutamine is energy sources utilized by rapidly proliferating cells. Glutamic acid the most abundant amino group in the human brain. L-Glutamine and Glutamine Powder plays a vital role to building and maintenance of muscle tissue.
more detail please visit: http://www.nutrovita.com/store/l-glutamine.htm

I hope this information will be useful for you.

Please check the posting dates before responding. This thread died 4 years ago.

If you've got something to say about glutamine, better to start a new thread than respond to one that old.

And your link is bogus - it's to a site that sells supplements.


FWIW, I use L-Glutamine in my recovery drinks...it seems to help my legs feel a bit fresher the day after a hard workout. I get mine at Wal-Mart (around $10 for 300 grams - less than half the cost of the price on that website).

s0crates
04-19-09, 11:08 PM
I just need to add something to this discussion since it seems to be brought back to life-

I'm not sure about the scientific proof, but I know when I used to work out heavily in the gym I used to be sore at least 3 times a week. After I started taking straight glutamine in powder form added to my protein shakes, I just never got sore again. It was like night and day. I'm not trying to sell you anything, nor do I know anything about special brands, but I can plain out vanilla tell you that it worked for me. It's also something I've been meaning to get my hands on again, think I will soon (but oh the price tag..)

SSP
04-19-09, 11:31 PM
I just need to add something to this discussion since it seems to be brought back to life-

I'm not sure about the scientific proof, but I know when I used to work out heavily in the gym I used to be sore at least 3 times a week. After I started taking straight glutamine in powder form added to my protein shakes, I just never got sore again. It was like night and day. I'm not trying to sell you anything, nor do I know anything about special brands, but I can plain out vanilla tell you that it worked for me. It's also something I've been meaning to get my hands on again, think I will soon (but oh the price tag..)

Glutamine is cheap...just don't buy it at over-priced places like GNC.

You can buy a 300 gram tub at Wal-Mart for $9.95, or 1000 grams for $27.99 at vitacost.com (http://www.vitacost.com/NSI-L-Glutamine-Powder-4-500-mg-2-2-lbs#IngredientFacts).

Oh, and yes...the stuff does work. I usually have 5-10 grams with my post-ride or evening protein shake, and find that it helps my legs feel fresher the next day.

youcoming
04-20-09, 06:59 AM
FWIW I use it during the riding season. I use to have awfull cramps at night and twitching all the time. Yes I drink a ton of water, use all the nutrition stuff, IE hammer gels, perpetuem, recovorite, etc. and still had problems. A giy I ride with recommended L-Glutamine and hey all my troubles went away. By no means scintific but it worked for me.

Tabagas_Ru
04-20-09, 07:15 AM
Acute L-glutamine ingestion does not improve maximal effort exercise.
Haub MD, Potteiger JA, Nau KL, Webster MJ, Zebas CJ. Journal of Sports Medicine and Physical Fitness. Turin: Sep 1998. Vol. 38, Iss. 3; pg. 240
Abstract (Summary)

BACKGROUND: L-glutamine (GLN) may have an ergogenic effect during exercise considering its base generating potential. We attempted to determine whether GLN ingestion influences acid-base balance and improves high intensity exercise performance. METHOD: Ten trained males performed five exercise bouts on a cycle ergometer at 100% of VO2 peak. The first four bouts were 60 sec in duration, while the fifth bout was continued to fatigue. Each bout was separated by 60 sec of recovery. The exercise bouts were initiated 90 min after ingesting 0.03 g.kg body mass-1 of either GLN or placebo (PLC). Venous blood samples were collected pre-ingestion (PRE-IN), pre-exercise (PRE-EX), and following bouts four (B4) and five (B5) and analyzed for pH, bicarbonate concentration (HCO3), and lactate concentration (La-). Time to fatigue for B5 was used as a performance measure. RESULTS: pH, [HCO3], and [La-] were not significantly different (p > 0.05) between conditions for PRE-IN, PRE-EX, B4, and B5. Time to fatigue was not significantly different between conditions and averaged 263.4 +/- 24.5 sec and 263.2 +/- 19.4 sec for the GLN and PLC trials, respectively. CONCLUSIONS: These data indicate that acute ingestion of L-glutamine does not enhance either buffering potential or high intensity exercise performance in trained males.


Therapeutic considerations of L-glutamine: a review of the literature.
Authors: Miller AL

The most abundant amino acid in the bloodstream, L-glutamine fulfills a number of biochemical needs. It operates as a nitrogen shuttle, taking up excess ammonia and forming urea. It can contribute to the production of other amino acids, glucose, nucleotides, protein, and glutathione. Glutamine is primarily formed and stored in skeletal muscle and lungs, and is the principal metabolic fuel for small intestine enterocytes, lymphocytes, macrophages, and fibroblasts. Supplemental use of glutamine, either in oral, enteral, or parenteral form, increases intestinal villous height, stimulates gut mucosal cellular proliferation, and maintains mucosal integrity. It also prevents intestinal hyperpermeability and bacterial translocation, which may be involved in sepsis and the development of multiple organ failure. L-glutamine use has been found to be of great importance in the treatment of trauma and surgery patients, and has been shown to decrease the incidence of infection in these patients. Cancer patients often develop muscle glutamine depletion, due to uptake by tumors and chronic protein catabolism. Glutamine may be helpful in offsetting this depletion; however, it may also stimulate the growth of some tumors. The use of glutamine with cancer chemotherapy and radiotherapy seems to prevent gut and oral toxic side-effects, and may even increase the effectiveness of some chemotherapy drugs.

s0crates
04-20-09, 11:17 AM
Ok so we can finally conclude that l-glutamine helps recovery yet does not help during physical exertion. Makes sense. I'm good with that, I think this thread can be laid to rest again. For recovery though, there's nothing better IMO.

u8myburger
04-22-09, 03:10 PM
Glutamine does NOT increase muscle size, nor does it increase muscle volume... Glutamine has only been shown to help increase the effectiveness of the immune system, help preserve lean mass, and can help assist with the recovery portion of the workout as it helps create a positive nitrogen balance within the body. Glutamine can also enter the Krebs Cycle as a non-carbohydrate source and form more ATP, but thats only during times of stravation

Nothing beats low-glycemic carbohydrates pre-workout and high-glycemic carbohydrates post-workout...

Try looking into waxy maize startch as part of your post-workout meal combined with whey protein 30 minutes after your workout with a carb/protein ratio of 3:1... I promise you'll have a energy to push harder the next day

Digital Gina
04-25-09, 10:45 AM
l-glutamine can be found in whey protein shakes. Ratio of 80% casein and 20% whey works best. A brand called muscle milk uses that combination, you can buy them seperately from Optimal Nutrition if you want higher grade stuff and mix it yourself