So I've tried just about every highly recommended saddle over the last few years and the SMP Glider and the Anatomica are by far the best. But between the two, the SMP wins hands down except for one big problem - after 80 miles or so, i get a sharp pain under my left sit-bone. I've noticed that on my Brooks and Anatomica that the left side is indeed indented more. Is there anyway to compensate with the SMP to avoid this pain in the, well you know. The Selle Anatomica is pretty great, but honestly the SMP is the only saddle I've used where I experience absolutely zero numbness, which is something I struggle with using almost all the other saddles, regardless of for, aft, or height.

That is an interesting dilemma. Do you know if you have one leg shorter than another? I have found as little a few millimeters can be enough to cause problems. I would recommend a good quality professional fitting. I went to a physical therapist who is also a triathlete.

Can use shims to tilt the saddle. I don't need to - just barely don't need to. Also, even a tiny bit of left or right nose is very crucial to me. In one direction it's OK a little off. Maybe better, I can't quite decide, but in the other direction nothing works right.

Shims - I had a brass tube about the right size to slip over the rails when cut in half. Shim under one rail, over the other. I'd tend to lightly superglue in place to the rail. Hobby shop tubing. I did this for people before. I might have the tubing still - fat chance of finding it in my shop!!!!

so aiming the saddle away from the pain works for some? i'm going to try this and report back.

Better to shim the cleat on you shoe (assuming here you have clipless). If you have a fit issue, a good professional fit will uncover any problems and give you the proper options to resolve them. By the way, have an An-atomica in my LD bike and think it's the greatest investment in comfort I've ever made.