Join Date: Apr 2003
Location: Pasadena, CA
Bikes: Litespeed Firenze / GT Avalanche
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The gear combination is not too extreme for the chain and cogs. Shimano says that you can use all of the cogs from the middle chainring. I don't think that is a reality without trim. I have no problem with Ultegra, but I do use the trim.
I would try to adjust it so if fits your riding style best. If you figure you can't use two cogs, you may be able to adjust to where you either don't use the big two, the small two, or the biggest and smallest.