When I am in my large front ring (50t - Shimano R700) and small rear cog (11t - Shimano DuraAce) I hear lot of chatter. Shifting is really smooth and precise, but very noisy in this combination. Any thougths as to why?
What kind of chatter? A visual inspection while turning the cranks would probably help most here - is the chain touching the 2nd-smallest cog? Is the chain hopping (a stiff link)? Is the derailer making any weird sudden movements? Does everything look "proper"?