This spoke must be in the right place or the valve hole will be in the wrong place, and the drilling of the rim may not match the angles of the spokes.
Rims are drilled either "right handed" or "left handed". This has to do with the relationship between the valve hole and the spoke holes. The spoke holes do not run down the middle of the rim, but are offset alternately from side to side.
The holes on the left side of the rim are for spokes that run to the left flange of the hub. with some rims the spoke hole just forward of the valve hole is offset to the left, with others it is offset to the right (as illustrated). Which type is "right handed" and which "left handed"? I have never met anyone who was willing to even make a guess!