Join Date: Sep 2008
Location: Loveland, CO
Bikes: Two LOOK 585s, one KG461
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If you buy expensive wheels to use with Campy 10, it's a no-brainer to get the Campy compatible cassette body on the rear hub. Shimano's cog spacing is a narrower 3.95mm, compared to Campy's 4.15mm.
If you're building the bike from scratch, Campy 11 speed is the way to go. It costs very little extra, but you do need to be sure that the rear hub is 11 speed compatible. Campy made no changes to their spline pattern, but the largest cog is about 1mm further to the left. That has caused some interference with a few hubs and prebuilt wheels.