Join Date: Aug 2005
Location: Pittsburgh, PA
Bikes: '''96 Litespeed Catalyst, '05 Litespeed Firenze, '06 Litespeed Tuscany, '12 Surly Pacer, All are 3x8,9 or 10. It is hilly around here!
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Assuming it's a single-speed, not a fixed gear, and you feel the vibration when walking the bike when the chain isn't moving, a tight chain may not be the cause.
Check both tires to be sure there isn't a bulge or something caught in the tread. If the tires are good, spin both wheels to see if there is damage or a flat spot in a rim from an impact. Finally, remove the wheels and spin them to see if the hubs are bad or an axle is bent.