Join Date: Jun 2007
Location: A Coffin Called Earth. or Toronto, ON
Bikes: Bianchi, Miyata, Dahon, Rossin
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it depends on your leg length and flexibility.
If you legs are long and you're flexible, then you're very unlikely to notice the difference. The only difference you might notice is that your cadence has dropped by single digits.
If your legs are short, even for 172.5mm cranks, then you will most likely notice it.
If your legs are short and you're not very flexible, then you will notice it.
and even then, there are variations in how the legs are proportioned, so you might feel it, or not.
For me, I notice I have a much easier time using 165mm cranks due to my limited flexibility.