Join Date: Apr 2009
Location: New Rochelle, NY
Bikes: too many bikes from 1967 10s (5x2)Frejus to a Sumitomo Ti/Chorus aluminum 10s (10x2), plus one non-susp mtn bike I use as my commuter
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While chainwear can cause vibration, it wouldn't have a sudden onset. Look for something broken or moved, either a broken spoke, or possibly a broken rear axle that allows the rear wheel to move slightly and rub under high chain tension.
You might check the axle.wheel movement theory by standing on a pedal with the front brake locked and watching for deflections in the wheel.
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