too many bikes from 1967 10s (5x2)Frejus to a Sumitomo Ti/Chorus aluminum 10s (10x2), plus one non-susp mtn bike I use as my commuter
It depends on which rear sprockets you use the most. If you're using it mostly with the outermost few in the rear, moving it outboard might make more sense. Think on terms of which of the three will yield the best chainline based on the gear combinations you actually spend the most time in, and set the chainline to favor those, while keeping it reasonable for the others.
In any case 1-2mm either way won't make a word of difference.