Join Date: Jul 2008
Location: Raleigh, NC
Bikes: 1972 Raleigh Twenty, mid-80's Trek
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As long as the cassette you want to mount on those wheels is Shimano (or SRAM) and the size is the same, as what was there before, I can't really see any problems other than axle spacing, which if it is off, any competent framebuilder or some shops should be able to do for you just fine. I think proper spacing for that kind of axle/hub is 135mm, but I'm not 100% positive. And just so long as you're using friction shifters that will move the derailleur all the way, and the rear derailleur you want to use will travel up and down all the sprockets... I say go for it.
But, that's about all I can tell you really.
I know the other members on the forum might be able to add, but, that's what I know on the subject.