Hi guys --
Picked up an extra set of wheels yesterday (open pros with ultegra hubs). Went with 32 spoke, as I have open sports with 105 hubs with 32 on the cross bike and have had zero issues...and the new wheels have butted spokes on top of it.
My thinking is that I keep the OEM set that came with the bike (2006 Kona JTS) for commutes and rides that involve dirt portions (there's one loop I love that includes about 5 miles of dirt), and use the new wheels for low rolling resistance, smaller tires. My current setup includes 700x38 semi-slick tires, and I'm thinking the new wheels should have 22 or 25 slicks. I'd like something tough and flat-resistant, but also quick and efficient as i'm going to start doing centuries this year.
Looked at conti gatorskins in 25, and specialized armadillos. I can afford something more expensive if worth it.
BTW, I'm 6'3 and about 225.