I lift weights twice a week and weigh 220 pounds. I ride five times a week for cardio fitness. Needless to say, paying hundreds of dollars to save a few ounces is a bit silly considering my size. I'm fairly convinced that component manufacturers do not design/engineer many of their high end road components for big guys. In fact I'd argue that they design most of their road components smaller framed people because (lack of) weight sells.
So...I'd like to hear some ideas from other clydesdales about components they prefer....my top three
1. Selle San Marco saddle
2. FSA Wing Pro bars
3. Easton EA90 SL wheelset