las999

I am looking to get a bike that will fit my 36" inseam and that will let me ride without putting pressure on my neck and shoulders (I can ride sitting straight up). It also needs to be heavy duty enough to carry my 280 pounds. Any suggestions. If possible, bike shop recommendations in western Oregon would be great too. I would be starting out riding on a bike trail or street riding.

Any ideas appreciated.

CliftonGK1

If you have similar trigger points as my fiancee, then aside from your shoulders/neck the one to be mindful of is the small of the back (where the nerves separate and head down the back of each leg).
Take a look at bikes that have a wider swept back handlebar, tall headtube/stem, and more of a foot forward ride position. This will assure that your weight is not on your arms/shoulders, allowing you to sit upright. It also gives you the ability to put both feet flat on the ground without stretching when you stop (something that is difficult on many traditional framed bikes.)

The Trek Navigator WSD or 7xxx hybrid WSD series might be a good starting point. The step-through frame design means you don't have to swing your leg over a top-tube to get on the bike.
Specialized's Globe Carmel might be another option. The suspension fork shouldn't be an issue since it's an upright cruiser and very little weight is actually over the front of the bike.

barturtle

You may wish to look into a recumbent bicycle, possibly one with under-seat steering. A recumbent trike might work well for you as well.

CliftonGK1

That was my first thought, but then I reconsidered. It's not the same for everyone, but for many with FMS a primary symptom is hypersensitivity of the "trigger points" (a series of 14 paired spots used as a one of the diagnostic indicators), many of which are between the shoulders and lower back. The seat on a 'bent might not be the best for that.
But as I said, FMS presents differently in everyone; maybe the OP would be fine with it.