I don't know much about wheels, and, seeing as how they take most of the abuse of typical road riding, and can be the Achilles heel of a Clyde's bike, I hope the forum can school me a bit.
Last weekend, LBS lent me a set of Madfiber wheels. They were wonderful, but they're also a lot more than I'm prepared to spend. Apart from having fun, they opened my mind to tubulars. When I returned them, I asked one of the mechanics to look into building me a set of tubbies at similar weight. The title shows what they came up with; these are $100 less and 100 grams lighter than Mavic Kyseriums. LBS says they've built lots of these, and that most of them are used for cyclocross.
These use DT Swiss hubs, bladed spokes (he told me which kind, which I forget, and showed me a set of Zipp wheels with the same spokes), and rims I can't remember the name of, either. The rims are about as shallow as they can possibly be.
LBS says they're very strong, and pretty aero. They've got better aerodynamics than my current wheels, but are no match for the Madfibers. Beyond that, though, they say I can't really tell unless I take them to a wind tunnel. And that'll cost more than both wheel sets combined! But they lent me a set, belonging to the shop's owner, and I think I've got them for at least a few days. They corner beautifully, and my bike weighs about 16 pounds with them.
I think I'm ultimately going to have them build me a set. Before I can go any further than just riding all the wheels they'll lend me, I have a lot to learn. So I'm hoping you folks can school me...?