Since my home town is practically unlivable now due to a population that instantly increased by 40% post hurricane Katrina, my wife is on me to move out of state. Being self-employed with clients nationwide, this is an available option.
Since I'm a "home boy" and haven't traveled much, I'm not familiar with too many other places.
Features we seek in a new home location include:
Year-round bicycling weather (taking into account the new, warmer winters)
Good medical quality and availability
Functioning public transportation system
Away from tornado-alley
Away from earthquake-prone areas
Away from hurricane-prone coasts