Just getting back into cycling. Bought a Giant Defy 1, upgrading several components. LBS adjusted the bike to fit me, taking several measurements, and plenty of time. Been riding quite a bit, and maybe I'm just not toughened up yet, but I'm still having some comfort issues. After a long ride, my palms are tender near the base of my thumb, despite gel gloves. I'm also experiencing pressure at the front edge of the sit bones. My weight isn't evenly distributed over the sit bones - more toward the front. I've thought about dropping the nose of the seat, but it's level now, and lowering the nose would force more weight on my already sore hands. Handlebars are already as high as they will go, and seat height is correct. Seat is also correct fore and aft, and it took changing the seat post to a zero offset post to get it there.
I'm hesitant to mess with the settings the bike shop took so long to get right, but I think there must be some minor adjustment that will make the seat and my hands more comfortable. Any ideas?