I was browsing through some failures on road bikes where many of the wheel failures happen when standing up to sprint.
It occurred to me that while smaller wheels are stronger, there is more. The moment (ie torque) exerted on the wheel components is smaller, too, due to the smaller diameter.
So there's a double whammy if you like - not only are the wheels stronger but under hard (or any) acceleration the stresses are lower.
Of course the bearings will wear faster due to rotating faster.