So today, I watched my odometer reach 275,000 on my '93 Accord. I'm impressed. This car has seen only synthetic oil with 7500 mile oil changes, timing belt + water pump changed every 100k miles, the usual stuff.
Whenever I see people deciding to send their cars to the junk yard, it's almost always because the body has rusted out badly, and is not worth fixing. Well there is no rust on this car, not even around the rear wheel. So I wonder, assuming your normal maintenance has been done, what do you expect will be the first major thing to fail? Something major that would make most people just give up on the car that is.